diff --git a/src/Controls/tests/TestCases.HostApp/Issues/Issue33331.cs b/src/Controls/tests/TestCases.HostApp/Issues/Issue33331.cs
new file mode 100644
index 000000000000..adec73688ab7
--- /dev/null
+++ b/src/Controls/tests/TestCases.HostApp/Issues/Issue33331.cs
@@ -0,0 +1,63 @@
+using Microsoft.Maui.Controls;
+
+namespace Maui.Controls.Sample.Issues;
+
+[Issue(IssueTracker.Github, 33331, "[Android] Picker IsOpen not reset when picker is dismissed", PlatformAffected.Android)]
+public class Issue33331 : ContentPage
+{
+    readonly List<string> _fruits = new() { "Apple", "Banana", "Mango", "Orange", "Pineapple" };
+    readonly Picker _testPicker;
+    readonly Label _isOpenLabel;
+
+    public Issue33331()
+    {
+        _testPicker = new Picker
+        {
+            AutomationId = "TestPicker",
+            Title = "Pick a fruit"
+        };
+        _testPicker.ItemsSource = _fruits;
+
+        var openButton = new Button
+        {
+            AutomationId = "OpenPickerButton",
+            Text = "Open Programmatically"
+        };
+        openButton.Clicked += OnOpenPicker;
+
+        _isOpenLabel = new Label
+        {
+            AutomationId = "IsOpenLabel",
+            Text = "IsOpen: False",
+            FontAttributes = FontAttributes.Bold
+        };
+
+        _testPicker.PropertyChanged += OnPickerPropertyChanged;
+
+        Content = new VerticalStackLayout
+        {
+            Padding = new Thickness(16),
+            Spacing = 12,
+            VerticalOptions = LayoutOptions.Center,
+            Children =
+                {
+                    _testPicker,
+                    openButton,
+                    _isOpenLabel
+                }
+        };
+    }
+
+    void OnPickerPropertyChanged(object sender, System.ComponentModel.PropertyChangedEventArgs e)
+    {
+        if (e.PropertyName == nameof(Picker.IsOpen))
+        {
+            _isOpenLabel.Text = $"IsOpen: {_testPicker.IsOpen}";
+        }
+    }
+
+    void OnOpenPicker(object sender, EventArgs e)
+    {
+        _testPicker.IsOpen = true;
+    }
+}
diff --git a/src/Controls/tests/TestCases.Shared.Tests/Tests/Issues/Issue33331.cs b/src/Controls/tests/TestCases.Shared.Tests/Tests/Issues/Issue33331.cs
new file mode 100644
index 000000000000..4d4ec0e29315
--- /dev/null
+++ b/src/Controls/tests/TestCases.Shared.Tests/Tests/Issues/Issue33331.cs
@@ -0,0 +1,30 @@
+using NUnit.Framework;
+using UITest.Appium;
+using UITest.Core;
+
+namespace Microsoft.Maui.TestCases.Tests.Issues;
+
+public class Issue33331 : _IssuesUITest
+{
+    public override string Issue => "[Android] Picker IsOpen not reset when picker is dismissed";
+
+    public Issue33331(TestDevice device) : base(device) { }
+
+    [Test]
+    [Category(UITestCategories.Picker)]
+    public void PickerCanBeOpenedProgrammatically()
+    {
+        App.WaitForElement("TestPicker");
+        App.WaitForElement("OpenPickerButton");
+        App.WaitForElement("IsOpenLabel");
+
+        var initialLabel = App.FindElement("IsOpenLabel").GetText();
+        Assert.That(initialLabel, Is.EqualTo("IsOpen: False"));
+
+        App.Tap("OpenPickerButton");
+        App.ClosePicker(windowsTapx: 50, windowsTapy: 50);
+        App.WaitForElement("IsOpenLabel");
+        var closedLabel = App.FindElement("IsOpenLabel").GetText();
+        Assert.That(closedLabel, Is.EqualTo("IsOpen: False"));
+    }
+}
\ No newline at end of file
diff --git a/src/Core/src/Handlers/Picker/PickerHandler.Android.cs b/src/Core/src/Handlers/Picker/PickerHandler.Android.cs
index 66a54812a6d0..bdb4d1bdad84 100644
--- a/src/Core/src/Handlers/Picker/PickerHandler.Android.cs
+++ b/src/Core/src/Handlers/Picker/PickerHandler.Android.cs
@@ -203,6 +203,7 @@ void OnDialogDismiss(object? sender, EventArgs e)
 
 			_dialog.DismissEvent -= OnDialogDismiss;
 			VirtualView.IsFocused = false;
+			VirtualView.IsOpen = false;
 			_dialog = null;
 		}
 
diff --git a/src/TestUtils/src/UITest.Appium/HelperExtensions.cs b/src/TestUtils/src/UITest.Appium/HelperExtensions.cs
index 2f5c62d15e59..6c86889be939 100644
--- a/src/TestUtils/src/UITest.Appium/HelperExtensions.cs
+++ b/src/TestUtils/src/UITest.Appium/HelperExtensions.cs
@@ -67,6 +67,34 @@ public static void RightClick(this IApp app, string element)
 			});
 		}
 
+		/// <summary>
+		/// Closes a picker dialog using platform-specific dismiss actions.
+		/// For Android, taps the "Cancel" button.
+		/// For iOS/MacCatalyst, taps the "Done" button.
+		/// For Windows, either taps coordinates (if provided) or the "Cancel" button.
+		/// </summary>
+		/// <param name="app">Represents the main gateway to interact with an app.</param>
+		/// <param name="x">Optional X coordinate for Windows tap. Default is 0.</param>
+		/// <param name="y">Optional Y coordinate for Windows tap. Default is 0.</param>
+		public static void ClosePicker(this IApp app, int windowsTapx = 0, int windowsTapy = 0)
+		{
+			if (app is AppiumAndroidApp)
+			{
+				app.Tap("Cancel");
+			}
+			else if (app is AppiumIOSApp || app is AppiumCatalystApp)
+			{
+				app.Tap("Done");
+			}
+			else if (app is AppiumWindowsApp)
+			{
+				if (windowsTapx != 0 || windowsTapy != 0)
+				{
+					app.TapCoordinates(windowsTapx, windowsTapy);
+				}
+			}
+		}
+
 		/// <summary>
 		/// Performs a down/press on the matched element, without a matching release
 		/// </summary>