diff --git a/eng/Version.Details.xml b/eng/Version.Details.xml
index 00d781b1461fe0..8301d951525f29 100644
--- a/eng/Version.Details.xml
+++ b/eng/Version.Details.xml
@@ -8,7 +8,7 @@
       <Uri>https://github.com/dotnet/msquic</Uri>
       <Sha>d7db669b70f4dd67ec001c192f9809c218cab88b</Sha>
     </Dependency>
-    <Dependency Name="Microsoft.NET.Runtime.Emscripten.2.0.23.Node.win-x64" Version="6.0.0-preview.7.21330.1">
+    <Dependency Name="Microsoft.NET.Workload.Emscripten.Manifest-6.0.100" Version="6.0.0-preview.7.21330.1">
       <Uri>https://github.com/dotnet/emsdk</Uri>
       <Sha>f5349765b7af1970c5b25cce4ed278544907cbe0</Sha>
     </Dependency>
diff --git a/eng/Versions.props b/eng/Versions.props
index 1c8ae0b1d33b0e..7f9f08fbe42740 100644
--- a/eng/Versions.props
+++ b/eng/Versions.props
@@ -178,7 +178,7 @@
     <runtimeosx1012x64MicrosoftNETCoreRuntimeMonoLLVMSdkVersion>11.1.0-alpha.1.21328.1</runtimeosx1012x64MicrosoftNETCoreRuntimeMonoLLVMSdkVersion>
     <runtimeosx1012x64MicrosoftNETCoreRuntimeMonoLLVMToolsVersion>11.1.0-alpha.1.21328.1</runtimeosx1012x64MicrosoftNETCoreRuntimeMonoLLVMToolsVersion>
     <!-- emscripten / Node -->
-    <MicrosoftNETRuntimeEmscripten2023Nodewinx64Version>6.0.0-preview.7.21330.1</MicrosoftNETRuntimeEmscripten2023Nodewinx64Version>
-    <MicrosoftNETRuntimeEmscriptenVersion>$(MicrosoftNETRuntimeEmscripten2023Nodewinx64Version)</MicrosoftNETRuntimeEmscriptenVersion>
+    <MicrosoftNETWorkloadEmscriptenManifest60100>6.0.0-preview.7.21330.1</MicrosoftNETWorkloadEmscriptenManifest60100>
+    <MicrosoftNETRuntimeEmscriptenVersion>$(MicrosoftNETWorkloadEmscriptenManifest60100)</MicrosoftNETRuntimeEmscriptenVersion>
   </PropertyGroup>
 </Project>
diff --git a/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Manifest/WorkloadManifest.json.in b/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Manifest/WorkloadManifest.json.in
index 4c50a08f007c82..eaf73dbd712be3 100644
--- a/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Manifest/WorkloadManifest.json.in
+++ b/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Manifest/WorkloadManifest.json.in
@@ -1,5 +1,8 @@
 {
   "version": "${WorkloadVersion}",
+  "depends-on": {
+    "Microsoft.NET.Workload.Emscripten": "${EmscriptenVersion}"
+  },
   "workloads": {
     "microsoft-net-sdk-blazorwebassembly-aot": {
       "description": "Browser Runtime native performance tools",
@@ -11,7 +14,7 @@
         "Microsoft.NET.Runtime.Emscripten.Python",
         "Microsoft.NET.Runtime.Emscripten.Sdk"
       ],
-      "extends": [ "microsoft-net-runtime-mono-tooling" ],
+      "extends": [ "microsoft-net-runtime-mono-tooling", "microsoft-net-sdk-emscripten" ],
       "platforms": [ "win-x64", "linux-x64", "osx-x64", "osx-arm64" ]
     },
     "microsoft-net-runtime-android": {
@@ -44,11 +47,13 @@
       "packs": [
         "Microsoft.NETCore.App.Runtime.Mono.ios-arm",
         "Microsoft.NETCore.App.Runtime.Mono.ios-arm64",
-        "Microsoft.NETCore.App.Runtime.Mono.iossimulator",
+        "Microsoft.NETCore.App.Runtime.Mono.iossimulator-arm64",
+        "Microsoft.NETCore.App.Runtime.Mono.iossimulator-x64",
         "Microsoft.NETCore.App.Runtime.Mono.iossimulator-x86",
         "Microsoft.NETCore.App.Runtime.AOT.Cross.ios-arm",
         "Microsoft.NETCore.App.Runtime.AOT.Cross.ios-arm64",
-        "Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator",
+        "Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator-arm64",
+        "Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator-x64",
         "Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator-x86"
       ],
       "extends": [ "microsoft-net-runtime-mono-tooling" ],
@@ -59,7 +64,8 @@
       "description": "MacCatalyst Mono Runtime and AOT Workload",
       "packs": [
         "Microsoft.NETCore.App.Runtime.Mono.maccatalyst",
-        "Microsoft.NETCore.App.Runtime.AOT.Cross.maccatalyst"
+        "Microsoft.NETCore.App.Runtime.AOT.Cross.maccatalyst-arm64",
+        "Microsoft.NETCore.App.Runtime.AOT.Cross.maccatalyst-x64"
       ],
       "extends": [ "microsoft-net-runtime-mono-tooling" ],
       "platforms": [ "osx-arm64", "osx-x64" ]
@@ -69,9 +75,11 @@
       "description": "tvOS Mono Runtime and AOT Workload",
       "packs": [
         "Microsoft.NETCore.App.Runtime.Mono.tvos-arm64",
-        "Microsoft.NETCore.App.Runtime.Mono.tvossimulator",
+        "Microsoft.NETCore.App.Runtime.Mono.tvossimulator-arm64",
+        "Microsoft.NETCore.App.Runtime.Mono.tvossimulator-x64",
         "Microsoft.NETCore.App.Runtime.AOT.Cross.tvos-arm64",
-        "Microsoft.NETCore.App.Runtime.AOT.Cross.tvossimulator"
+        "Microsoft.NETCore.App.Runtime.AOT.Cross.tvossimulator-arm64",
+        "Microsoft.NETCore.App.Runtime.AOT.Cross.tvossimulator-x64"
       ],
       "extends": [ "microsoft-net-runtime-mono-tooling" ],
       "platforms": [ "osx-arm64", "osx-x64" ]
@@ -81,7 +89,7 @@
       "description": "Shared native build tooling for Mono runtime",
       "packs": [
         "Microsoft.NET.Runtime.RuntimeConfigParser.Task",
-        "Microsoft.NET.Runtime.MonoAOTCompiler.Task",
+        "Microsoft.NET.Runtime.MonoAOTCompiler.Task"
       ],
     }
   },
@@ -154,13 +162,13 @@
         "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.android-arm64"
       }
     },
-    "Microsoft.NETCore.App.Runtime.Mono.maccatalyst": {
+    "Microsoft.NETCore.App.Runtime.Mono.maccatalyst-arm64": {
+      "kind": "framework",
+      "version": "${PackageVersion}",
+    },
+    "Microsoft.NETCore.App.Runtime.Mono.maccatalyst-x64": {
       "kind": "framework",
       "version": "${PackageVersion}",
-      "alias-to": {
-        "osx-arm64": "Microsoft.NETCore.App.Runtime.Mono.maccatalyst-arm64",
-        "osx-x64": "Microsoft.NETCore.App.Runtime.Mono.maccatalyst-x64"
-      }
     },
     "Microsoft.NETCore.App.Runtime.Mono.ios-arm" : {
       "kind": "framework",
@@ -170,54 +178,67 @@
       "kind": "framework",
       "version": "${PackageVersion}"
     },
-    "Microsoft.NETCore.App.Runtime.Mono.iossimulator" : {
+    "Microsoft.NETCore.App.Runtime.Mono.iossimulator-arm64" : {
       "kind": "framework",
-      "version": "${PackageVersion}",
-      "alias-to": {
-        "osx-arm64": "Microsoft.NETCore.App.Runtime.Mono.iossimulator-arm64",
-        "osx-x64": "Microsoft.NETCore.App.Runtime.Mono.iossimulator-x64"
-      }
+      "version": "${PackageVersion}"
+    },
+    "Microsoft.NETCore.App.Runtime.Mono.iossimulator-x64" : {
+      "kind": "framework",
+      "version": "${PackageVersion}"
     },
     "Microsoft.NETCore.App.Runtime.Mono.iossimulator-x86" : {
       "kind": "framework",
-      "version": "${PackageVersion}",
-      "alias-to": {
-        "osx-x64": "Microsoft.NETCore.App.Runtime.Mono.iossimulator-x86"
-      }
+      "version": "${PackageVersion}"
     },
     "Microsoft.NETCore.App.Runtime.AOT.Cross.tvos-arm64": {
       "kind": "Sdk",
       "version": "${PackageVersion}",
       "alias-to": {
-        "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.tvos-arm64",
         "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.tvos-arm64",
+        "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.tvos-arm64"
       }
     },
     "Microsoft.NETCore.App.Runtime.Mono.tvos-arm64" : {
       "kind": "framework",
       "version": "${PackageVersion}"
     },
-    "Microsoft.NETCore.App.Runtime.Mono.tvossimulator" : {
+    "Microsoft.NETCore.App.Runtime.Mono.tvossimulator-arm64" : {
       "kind": "framework",
+      "version": "${PackageVersion}"
+    },
+    "Microsoft.NETCore.App.Runtime.Mono.tvossimulator-x64" : {
+      "kind": "framework",
+      "version": "${PackageVersion}"
+    },
+    "Microsoft.NETCore.App.Runtime.AOT.Cross.maccatalyst-arm64": {
+      "kind": "Sdk",
       "version": "${PackageVersion}",
       "alias-to": {
-        "osx-arm64": "Microsoft.NETCore.App.Runtime.Mono.tvossimulator-arm64",
-        "osx-x64": "Microsoft.NETCore.App.Runtime.Mono.tvossimulator-x64"
+        "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.maccatalyst-arm64",
+        "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.maccatalyst-arm64"
       }
     },
-    "Microsoft.NETCore.App.Runtime.AOT.Cross.maccatalyst": {
+    "Microsoft.NETCore.App.Runtime.AOT.Cross.maccatalyst-x64": {
       "kind": "Sdk",
       "version": "${PackageVersion}",
       "alias-to": {
-        "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.maccatalyst-arm64",
+        "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.maccatalyst-x64",
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.maccatalyst-x64"
       }
     },
-    "Microsoft.NETCore.App.Runtime.AOT.Cross.tvossimulator": {
+    "Microsoft.NETCore.App.Runtime.AOT.Cross.tvossimulator-arm64": {
       "kind": "Sdk",
       "version": "${PackageVersion}",
       "alias-to": {
         "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.tvossimulator-arm64",
+        "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.tvossimulator-arm64"
+      }
+    },
+    "Microsoft.NETCore.App.Runtime.AOT.Cross.tvossimulator-x64": {
+      "kind": "Sdk",
+      "version": "${PackageVersion}",
+      "alias-to": {
+        "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.tvossimulator-x64",
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.tvossimulator-x64"
       }
     },
@@ -234,14 +255,22 @@
       "version": "${PackageVersion}",
       "alias-to": {
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.ios-arm64",
-        "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.ios-arm64",
+        "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.ios-arm64"
       }
     },
-    "Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator": {
+    "Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator-arm64": {
       "kind": "Sdk",
       "version": "${PackageVersion}",
       "alias-to": {
         "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.iossimulator-arm64",
+        "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.iossimulator-arm64"
+      }
+    },
+    "Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator-x64": {
+      "kind": "Sdk",
+      "version": "${PackageVersion}",
+      "alias-to": {
+        "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.iossimulator-x64",
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.iossimulator-x64"
       }
     },
@@ -249,6 +278,7 @@
       "kind": "Sdk",
       "version": "${PackageVersion}",
       "alias-to": {
+        "osx-arm64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.iossimulator-x86",
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.iossimulator-x86"
       }
     },
@@ -265,35 +295,6 @@
     "Microsoft.NETCore.App.Runtime.Mono.browser-wasm" : {
       "kind": "framework",
       "version": "${PackageVersion}"
-    },
-    "Microsoft.NET.Runtime.Emscripten.Node" : {
-      "kind": "Sdk",
-      "version": "${EmscriptenVersion}",
-      "alias-to": {
-        "win-x64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Node.win-x64",
-        "linux-x64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Node.linux-x64",
-        "osx-x64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Node.osx-x64",
-        "osx-arm64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Node.osx-x64"
-      }
-    },
-    "Microsoft.NET.Runtime.Emscripten.Python" : {
-      "kind": "Sdk",
-      "version": "${EmscriptenVersion}",
-      "alias-to": {
-        "win-x64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Python.win-x64",
-        "osx-x64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Python.osx-x64",
-        "osx-arm64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Python.osx-x64"
-      }
-    },
-    "Microsoft.NET.Runtime.Emscripten.Sdk" : {
-      "kind": "Sdk",
-      "version": "${EmscriptenVersion}",
-      "alias-to": {
-        "win-x64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Sdk.win-x64",
-        "linux-x64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Sdk.linux-x64",
-        "osx-x64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Sdk.osx-x64",
-        "osx-arm64": "Microsoft.NET.Runtime.Emscripten.2.0.23.Sdk.osx-x64"
-      }
     }
   }
-}
\ No newline at end of file
+}
diff --git a/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Manifest/WorkloadManifest.targets b/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Manifest/WorkloadManifest.targets
index ab039e9a716784..56650214b27598 100644
--- a/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Manifest/WorkloadManifest.targets
+++ b/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Manifest/WorkloadManifest.targets
@@ -24,14 +24,17 @@
     <ImportGroup Condition="'$(TargetPlatformIdentifier)' == 'ios' and $([MSBuild]::IsOSPlatform('osx'))">
         <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.ios-arm" />
         <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.ios-arm64" />
-        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator" />
+        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator-arm64" />
+        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator-x64" />
+        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.iossimulator-x86" />
     </ImportGroup>
 
     <ImportGroup Condition="'$(TargetPlatformIdentifier)' == 'maccatalyst'">
         <Import Project="Sdk.props" Sdk="Microsoft.NET.Runtime.RuntimeConfigParser.Task" />
     </ImportGroup>
     <ImportGroup Condition="'$(TargetPlatformIdentifier)' == 'maccatalyst' and $([MSBuild]::IsOSPlatform('osx'))">
-        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.maccatalyst" />
+        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.maccatalyst-arm64" />
+        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.maccatalyst-x64" />
     </ImportGroup>
 
     <ImportGroup Condition="'$(TargetPlatformIdentifier)' == 'tvos'">
@@ -39,14 +42,12 @@
     </ImportGroup>
     <ImportGroup Condition="'$(TargetPlatformIdentifier)' == 'tvos' and $([MSBuild]::IsOSPlatform('osx'))">
         <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.tvos-arm64" />
-        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.tvossimulator" />
+        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.tvossimulator-arm64" />
+        <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.tvossimulator-x64" />
     </ImportGroup>
 
     <ImportGroup Condition="'$(RuntimeIdentifier)' == 'browser-wasm' and '$(UsingBrowserRuntimeWorkload)' == 'true'">
         <Import Project="Sdk.targets" Sdk="Microsoft.NET.Runtime.WebAssembly.Sdk" />
-        <Import Project="Sdk.props" Sdk="Microsoft.NET.Runtime.Emscripten.Python" Condition="!$([MSBuild]::IsOsPlatform('Linux'))" />
-        <Import Project="Sdk.props" Sdk="Microsoft.NET.Runtime.Emscripten.Node" />
-        <Import Project="Sdk.props" Sdk="Microsoft.NET.Runtime.Emscripten.Sdk" />
         <Import Project="Sdk.props" Sdk="Microsoft.NETCore.App.Runtime.AOT.Cross.browser-wasm" />
     </ImportGroup>
 </Project>