We occasionally see folks trying to use OAS with multipart/mixed, which does not support it. But it would not be hard to define a mapping along the lines of multipart/form-data but with more of an array model. See also discussion #2599. I think @jeremyfiel also has experience with this.
[EDIT: See also multipart/x-mixed-replace which AFAICT does not have a usable specification as WHATWG explicitly states in that section that there spec "describes processing rules for web browsers" and relegates everything else to multipart/mixed... I guess non-web-browsers aren't supposed to process it? 😒 ]